@layer reset{*,:before,:after{box-sizing:border-box}html{-webkit-text-size-adjust:100%;scrollbar-gutter:stable}body{margin:0;padding:0}img,picture,svg,video,canvas{max-width:100%;height:auto;display:block}button,input,textarea,select{font:inherit}}@layer base{:root{color-scheme:light;--font-body:system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;--color-background-gradient:radial-gradient(circle at 85% 15%, var(--color-accent-soft), transparent 18rem), radial-gradient(circle at 10% 100%, #07598514, transparent 14rem), linear-gradient(135deg, var(--color-surface), var(--color-surface-muted));--color-background:#f7f9fb;--color-background-muted:#eef5f8;--color-surface:#fff;--color-surface-muted:#f1f7fa;--color-text:#172033;--color-muted:#5f6b7a;--color-border:#d8e2ea;--color-link:#075985;--color-accent:#0f766e;--color-accent-soft:rgb(from var(--color-accent) r g b / .1);--color-yes:#007e47;--color-yes-light:rgb(from var(--color-yes) r g b / .07);--color-no:#b42318;--color-no-light:rgb(from var(--color-no) r g b / .06);--color-alert:#ffea00;--color-alert-light:rgb(from var(--color-alert) r g b / .33);--color-card:var(--color-surface);--space-1:.25rem;--space-2:.5rem;--space-3:.75rem;--space-4:1rem;--space-5:1.25rem;--space-6:1.5rem;--space-8:2rem;--space-10:2.5rem;--page-width:72rem;--text-width:72ch;--page-gutter:1rem;--border-width:1px}html{font-family:var(--font-body);color:var(--color-text);line-height:1.5}body{background:var(--color-background-gradient);min-height:100vh;color:var(--color-text);grid-template-rows:auto auto 1fr auto;display:grid}body>header,body>main,body>footer{width:min(100% - calc(var(--page-gutter) * 2), var(--page-width));margin-inline:auto}body>header{width:100%;max-width:none;padding:var(--space-3) max(var(--page-gutter), calc((100vw - var(--page-width)) / 2));border-bottom:var(--border-width) solid var(--color-border);background-color:rgb(from var(--color-surface) r g b / .92);gap:var(--space-4);justify-content:space-between;align-items:center;display:flex}body>header>div>nav>ul{gap:var(--space-6);flex-direction:row;list-style-type:none;display:flex}body>header>div>nav>ul>li>a{color:var(--color-text);text-decoration:none}.current-page{text-underline-offset:var(--space-2);color:var(--color-accent);text-decoration:underline}@media (width>=48rem){body>header>div>nav>ul{flex-direction:row}}.home-main,body>main{padding-block:var(--space-8);gap:var(--space-6);flex-direction:column;display:flex}body>footer{width:100%;max-width:none;padding:var(--space-6) max(var(--page-gutter), calc((100vw - var(--page-width)) / 2));border-top:var(--border-width) solid var(--color-border);color:var(--color-background);background-color:var(--color-text);font-size:.95rem}body>footer a{color:var(--color-background)}article>header{margin-block-end:var(--space-8)}section{padding:var(--space-6) 0}:where(h1,h2,h3,h4){line-height:1.2}h1{margin-block:0 var(--space-4);font-size:clamp(2rem,6vw,3rem)}h2{margin-block:0 var(--space-4);font-size:clamp(1.5rem,4vw,2rem)}h3{margin-block:var(--space-6) var(--space-3);font-size:1.25rem}h4{margin-block:var(--space-5) var(--space-2);font-size:1rem}:where(p,ul,ol,dl,table,blockquote){margin-block:0 var(--space-4)}:where(p,ul,ol,dl,table,blockquote):last-child{margin-block-end:0}:where(ul,ol){padding-inline-start:1.5rem}li{margin-block-start:var(--space-2)}:where(p,li,dd,td){overflow-wrap:break-word}a{color:var(--color-link);text-underline-offset:.15em}a:hover{text-decoration-thickness:.12em}:where(nav ul){padding-inline-start:1.25rem}nav a{text-decoration-thickness:.08em}table{border-collapse:collapse;width:100%;font-size:.95rem}th,td{padding:var(--space-2);border:var(--border-width) solid var(--color-border);text-align:left;vertical-align:top}th{background:var(--color-surface)}blockquote{border-inline-start:4px solid var(--color-border);color:var(--color-muted);padding-inline-start:var(--space-4)}hr{border:0;border-top:var(--border-width) solid var(--color-border);margin-block:var(--space-8)}code{font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace;font-size:.95em}pre{padding:var(--space-4);background:var(--color-surface);border:var(--border-width) solid var(--color-border);overflow-x:auto}:target{scroll-margin-block-start:var(--space-8)}:focus-visible{outline-offset:3px;outline:3px solid}@media (width>=48rem){:root{--page-gutter:2rem}body>main{padding-block:var(--space-10)}}*{scroll-behavior:smooth}@media (prefers-reduced-motion:reduce){*,:before,:after{scroll-behavior:auto!important;transition-duration:.001ms!important;animation-duration:.001ms!important;animation-iteration-count:1!important}}@media (prefers-contrast:more){:root{--color-border:currentColor}a{text-decoration-thickness:.15em}}@media (forced-colors:active){a{text-decoration:underline}}@media print{body{color:#000;background:#fff}body>header,body>footer,nav{display:none}body>main{width:auto;padding:0}a{color:#000}a[href^=http]:after{content:" (" attr(href) ")";overflow-wrap:break-word}}html{interpolate-size:allow-keywords}details::details-content{opacity:0;transition-behavior:allow-discrete;height:0;transition:opacity .4s,height .4s,content-visibility .4s;overflow:hidden}details[open]::details-content{opacity:1;height:auto}}@layer components{.skip-link{top:var(--space-2);left:var(--space-2);z-index:10;padding:var(--space-3) var(--space-4);border-radius:var(--radius-sm);background:var(--color-text);color:var(--color-background);font-weight:700;position:absolute;transform:translateY(-150%)}.skip-link:focus{transform:translateY(0)}.logo>a>img{width:2rem}#study-hero{padding:0 0 var(--space-6) 0;gap:var(--space-6);background-image:url(/_astro/brain.5igxgThO.png);background-position:100%;background-repeat:no-repeat;background-size:contain;border-top:0 solid #000;min-height:24rem;display:grid}.eyebrow{color:var(--color-accent);font-size:1.2rem;font-weight:700}#study-hero a{padding:var(--space-3) var(--space-6);background-color:var(--color-link);color:var(--color-background);border-radius:var(--space-2);font-weight:700;text-decoration:none}#conditions-list{padding:var(--space-6);border-radius:var(--space-6)}.snapshot-grid{gap:var(--space-6);flex-direction:column;display:flex}@media (width>=48rem){.snapshot-grid{flex-direction:row}}.snapshot-grid>div{width:100%;height:100%;padding:var(--space-6);border-radius:var(--space-2);gap:var(--space-3);border:1px solid var(--color-accent);text-align:center;align-content:start;display:grid}.snapshot-grid dt{color:var(--color-muted);font-size:.875rem;font-weight:700}.snapshot-grid dd{margin:var(--space-1) 0 0;font-size:1.125rem;font-weight:700}#conditions-list{background-color:var(--color-background-muted)}#sponsor-info{padding:var(--space-6);background-color:var(--color-background);border:var(--border-width) solid var(--color-border);border-radius:var(--space-6)}.card-group{grid-template-columns:repeat(auto-fit,minmax(16rem,1fr));justify-content:start;align-items:stretch;gap:1rem;display:grid}@media (width>=48rem){.card-group{grid-template-columns:repeat(auto-fit,minmax(21rem,21rem));align-items:start;gap:1rem;display:grid}}.card{background-color:var(--color-card);width:100%;height:100%;padding:var(--space-6);border-radius:var(--space-2);gap:var(--space-3);border:1px solid var(--color-border);align-content:start;display:grid}.card h3,.card h4,.card p{margin:0}.card details{color:var(--color-text);gap:var(--space-2);align-content:start;display:grid}.card details summary{color:var(--color-link)}.card-yes{background-color:var(--color-yes-light)}.card-yes h3{color:var(--color-yes)}.card-no{background-color:var(--color-no-light)}.card-no h3{color:var(--color-no)}#eligibility-criteria .card-group{grid-template-columns:repeat(auto-fit,minmax(16rem,1fr))}#reference-list ol{gap:1rem;display:grid}@media (width>=48rem){#reference-list ol{margin-left:var(--space-6)}}.generator-panel{max-width:var(--text-width);padding-block-start:var(--space-6)}.generator-form{gap:var(--space-3);margin-block-start:var(--space-6);display:grid}.generator-form label{font-weight:700}.generator-form-row{gap:var(--space-3);display:grid}.generator-form input{width:100%;min-height:3rem;padding:var(--space-3) var(--space-4);border:var(--border-width) solid var(--color-border);border-radius:var(--space-2);background:var(--color-surface);color:var(--color-text)}.generator-form button,.button-link{min-height:3rem;padding:var(--space-3) var(--space-6);border-radius:var(--space-2);background-color:var(--color-link);color:var(--color-background);cursor:pointer;border:0;font-weight:700;text-decoration:none}.generator-form button:hover,.button-link:hover{text-decoration:underline .12em}.form-note,.preview-note,#generator-status{color:var(--color-muted);font-size:.95rem}#generator-status:not(:empty){margin-block-start:var(--space-4)}.preview-toolbar{gap:var(--space-3);padding:var(--space-4);border:var(--border-width) solid var(--color-border);border-radius:var(--space-2);background:rgb(from var(--color-surface) r g b / .82);flex-wrap:wrap;justify-content:space-between;align-items:center;display:flex}.preview-actions{gap:var(--space-3);flex-wrap:wrap;display:flex}.secondary-button{padding:var(--space-2) var(--space-4);border:0 solid var(--color-text);border-radius:var(--space-2);background:var(--color-surface);color:var(--color-text);cursor:pointer;font-weight:700}.secondary-button:hover{text-decoration:underline}.empty-state{padding:var(--space-6);border:var(--border-width) solid var(--color-border);border-radius:var(--space-2);background-color:var(--color-card)}.criteria-meta{margin-block-end:var(--space-6)}.criteria-meta dl{gap:var(--space-3);display:grid}.criteria-meta dt{color:var(--color-muted);font-size:.875rem;font-weight:700}.criteria-meta dd{margin:0;font-weight:700}.hidden{display:none!important}@media (width>=48rem){.generator-form-row{grid-template-columns:minmax(16rem,24rem) auto;align-items:end}.criteria-meta dl{grid-template-columns:repeat(4,minmax(0,1fr))}}.secondary-button:disabled,.generator-form button:disabled{cursor:progress;opacity:.7}.preview-banner{width:100vw;padding:var(--space-3) max(var(--page-gutter), calc((100vw - var(--page-width)) / 2));background-color:var(--color-alert-light);margin-inline:calc(50% - 50vw)}.preview-banner-inner{gap:var(--space-3);flex-wrap:wrap;justify-content:space-between;align-items:center;display:flex}.preview-banner .preview-note{color:var(--color-text);margin:0}.preview-close{padding-inline:var(--space-3)}.section-nav ul{gap:var(--space-3);flex-wrap:wrap;margin:0;padding:0;list-style:none;display:flex}.section-nav a{padding:var(--space-2) var(--space-3);border:var(--border-width) solid var(--color-border);border-radius:var(--space-2);background:var(--color-surface);font-weight:700;text-decoration:none;display:inline-flex}}@layer theme,utilities;